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Organization: MRC Functional Genomics Unit (FGU)

Location: Oxford, UK

Field: Genomics

Requirements:

PhD/DPhil in the field of computational biology, bioinformatics, statistical genetics or comparative genomics (E) Training in statistical methods appropriate for biological research (D)

Abstract:

The MRC Unit is embedded within the Department of Physiology, Anatomy and Genetics at the University of Oxford, and is a world-renowned centre for comparative genomics and research into neuromuscular and neurodegenerative disorders. We offer excellent computational and laboratory facilities in the recently-opened Henry Wellcome Building of Gene Function.

Description:

The successful applicant will join a research group that has established an international reputation for genome-scale data analyses, disease genomics, and function prediction for coding or non-coding sequence.  This is one of three MRC-funded posts which form the core of Professor Chris Ponting’s Computational Genomics group within the MRC Functional Genomics Unit in Oxford.  The post will provide core biological and computational expertise in disease and trait genomics and in next-generation sequence analysis, and thus will contribute to a shift in the group’s emphasis from comparing genomes among species, to comparing those within a population; from evolution to molecular mechanism; and, from function to molecular pathoaetiology.
This post will also sit adjacent to Professor Ponting’s Strategic Programme in Computational Genomics Analysis and Training (CGAT) within the MRC Functional Genomics Unit in Oxford. CGAT’s mission is to provide substantial expertise and added-value to funded research UK-wide, whilst training a future generation of genome biologists.
Informal enquiries can be made to Prof. Chris Ponting at chris.ponting@dpag.ox.ac.uk. For further information about the MRC please visit www.mrc.ac.uk
Working relationships
The post-holder will report directly to Prof Chris Ponting, but s/he will also work closely with other research fellows, post-doctoral scientists, and laboratory support staff in the Ponting group and in CGAT, and with others working within the Department of Physiology, Anatomy and Genetics.  The post-holder may also contribute to the supervision of DPhil (PhD) students.
Further interaction with other members of the Unit and University will be encouraged and as necessary there may be a need to establish working relationships with collaborators in other MRC Units or parts of the University Medical Sciences Division, or other groups nationally or worldwide.
Main duties and responsibilities
• Participate in the group’s research programme, with particular emphasis on developing computational approaches to identifying and characterising genes and variants that underlie human diseases.
• To support and maintain internal and external collaborations that form part of the group’s research within the University of Oxford.
• Attend lab meetings and regularly report on studies and results to the group leader.
• Assist in the supervision of research students, and provide technical advice/guidance to other members of the group.
• Participate in Unit meetings and those of the wider MRC / University community.
• Disseminate research results through the publication of peer-reviewed papers and oral/poster presentations at national and international scientific meetings.
• Adhere to good laboratory practice and safety procedures within the Unit and University host Department.
• Contribute to the Unit’s strategy for public communication of science and to the application or exploitation of the research findings.
• Keep adequate written reports (electronic or otherwise) of work undertaken, participate in group meetings, maintain collaborations, keep abreast of the literature in the field of functional genomics, and prepare papers for publication and presentation at meetings.
• Maintain dedicated computer, whilst liaising with the Unit’s Research Support-Systems Administrator to optimise use of computational resources.
• Assist in the genomics and bioinformatics training of other members of the laboratory and the University.
 
Previous work experience
Experience of administering a Linux system (E).
Experience of sequence analysis tools in biological research, current bioinformatics tools and resources (D). Knowledge of general computational methods (D).
Experience of scripting (e.g. Perl), in addition to advanced UNIX. (E)
Experience in functional genomics and in method development (D
 
Personal style and behaviour
Team player, strong sense of research ethics, reliable, organised, trustworthy. Proven ability to provide help/advice on techniques to others in a computational genomics environment would be advantageous.
 
  
Additional Details   
   
Benefits include a flexible pay and reward policy, excellent holiday entitlement, MRC final salary pension scheme. 
  
How To Apply   
   
The closing date for applications is Tuesday 8th March 2011.  The interview for this vacancy will take place on Monday 21st and Tuesday 22nd March 2011.
Only online applications will be accepted.  Applicants who would like to receive this advert in an alternative format (e.g. large print, Braille, audio or hard copy), or who are unable to apply online should contact us by telephone on 01793 867003.  Please quote the appropriate reference number when calling. 
 

Salary: £35,935 to £39,723 per annum
Grade: MRC Band 3
Contract Type: Open-Ended
Hours: Full Time 
 
 

 
 

Deadline: 08-03-2011

Contacts:

Link: http://www.mrc.ac.uk

Link: http://www.mrcfgu.ox.ac.uk

Email: chris.ponting@dpag.ox.ac.uk

Phone number: 01793 867003

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