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Organization: Job Radboud University Nijmegen Medical Centre (RUN MC)

Location: Nijmegen, Netherlands

Field: Biomedical Sciences

Requirements:

You should be a creative and enthusiastic researcher with a MSc or PhD degree in Computer Science, Physics, Engineering or Biomedical Sciences or similar, with a clear interest to develop image analysis algorithms and an affinity with medical topics. The postdoc should have a strong track record. Good communication skills, and expertise in software development, preferably in C++, are essential.

Abstract:

Computed Tomography (CT) imaging of the brain is an important step for diagnosis and treatment planning. The latest advances in CT technology enable dynamic scanning or perfusion imaging covering the complete brain with a temporal resolution of 0.35 seconds.

Description:

Computed Tomography (CT) imaging of the brain is an important step for diagnosis and treatment planning. The latest advances in CT technology enable dynamic scanning or perfusion imaging covering the complete brain with a temporal resolution of 0.35 seconds. This means you can see the in-flow and out-flow of the blood in real-time and obtain detailed functional information in addition to the anatomical information of the brain. See the attached webpage for an example of the cerebral blood flow (figure left) and a reconstructed static angiography image showing the cerebral vasculature (figure right). We will have the most advanced CT scanner with large coverage installed in our hospital by mid 2011 and we closely collaborate with the manufacturer, Toshiba Medical Systems Corporation from Japan. Currently only two of these scanners have been installed in the Netherlands, and Nijmegen will be the third. To fully exploit the potential of perfusion imaging, many issues need to be addressed on all levels from acquisition to image interpretation. These include radiation dose reduction strategies by scan protocol optimization, registration to compensate for patient movement, radiation dose reduction strategies by the development of noise filtering techniques, image reconstructions techniques, and high level image analysis algorithms for example the automatic detection of small aneurysms. All these technical studies are carried out in conjunction with clinical studies. Initially we focus on perfusion imaging of the brain, but soon we will extend our research to other body areas. Considering the large amount of research to be carried out for this project, two research positions are offered.

Deadline: 25-02-2011

Contacts:

Email: r.manniesing@rad.umcn.nl

Email: b.vanginneken@rad.umcn.nl

Phone number: +31 (0)24 3619811

Phone number: +31 (0)24 3616708

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