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Early Stage Researcher: "Transcriptomic and metabolomic approaches to discover biomarkers of exposure and effect of flame retardant chemicals".
Organization: University of Birmingham - School of Biosciences
Location: Birmingham, UK
Field: Biosciences
Requirements:
Applicants should complete an application form, available from the website detailed below, provide an up-to-date CV and 1-page statement of motivation that explains your interests in this project, why you are the ideal candidate and your future plans, together with the names of two scientific referees. Informal enquiries should be directed to: Prof. Mark Viant (m.viant@bham.ac.uk) or Prof. Kevin Chipman (j.k.chipman@bham.ac.uk), School of Biosciences, University of Birmingham.
Abstract:
This Early Stage Researcher position is funded by the European Union as part of the INFLAME Marie Curie Initial Training Network on indoor contamination with flame retardant chemicals. INFLAME will further understanding of how and to what extent flame retardant (FR) chemicals used in every-day materials enter humans and of the risk to health that such exposure presents.
Description:
The successful applicant will utilise cell culture models, transcriptomics (Agilent microarrays) and metabolomics (FT-ICR mass spectrometry and 1H NMR spectroscopy) to elucidate the mechanisms via which FRs exert toxicity. The toxic effects of FR-contaminated air and dust exposures will be studied in cell culture models. Further in vitro and in vivo models will be investigated in collaboration with other partners in INFLAME. The project will involve considerable bioinformatics and statistics to "mine" the omics datasets, and considerable biochemistry to interpret the mechanisms of molecular toxicity. Most research activities will take place within the large and thriving School of Biosciences of the University of Birmingham, which has an international track record in toxicology. The successful applicant is expected to register for a PhD degree.
Reference: 47312
Deadline: 02-03-2011
Contacts:
Link: http://www.hr.bham.ac.uk/jobs
Phone number: 0121 415 9000
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