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PhD student Nephrology

Organization: Radboud University Nijmegen Medical Centre (RUN MC)

Location: St Radbound, Netherlands

Field: Nephrology

Requirements:

We are looking for an enthusiastic PhD student with an M.Sc. in Molecular Life Sciences, (Medical) Biology, Biomedical Sciences or similar. Your working style can be described as independent and well-structured, and you are a team player. You have special interest in translational type of research. Last but not least, you have a strong motivation to become a successful scientist. Applicants are requested to send a letter of intent outlining their specific interest in the position and a curriculum vitae preferably including references.

Abstract:

We are looking for an enthusiastic PhD student with an M.Sc. in Molecular Life Sciences, (Medical) Biology, Biomedical Sciences or similar. Your working style can be described as independent and well-structured, and you are a team player. You have special interest in translational type of research. Last but not least, you have a strong motivation to become a successful scientist. Applicants are requested to send a letter of intent outlining their specific interest in the position and a curriculum vitae preferably including references.

Description:

The infectious history of a renal transplant candidate strongly influences his innate and adaptive immune responsiveness to allo-antigens. A better understanding of the interplay between viral pathogens and the allo-immune response will therefore improve the results of  renal transplantation. Highlights of the current project are:

  • Characterization of the interplay between antiviral (e.g. CMV) and allo-immune immune responses in the allograft, as reflected in tissue pathology and urinary composition
  • Identification of urinary markers that can be used for non-invasive monitoring of virally induced innate and adaptive immune responses in the renal graft
  • Discovery of novel urinary biomarkers of graft injury upon viral (CMV and BKV) infection
  • Application of a wide range of approaches & techniques, with emphasis on proteomics, to answer the research questions
  • Strong collaboration with partners within the research consortium, in Nijmegen,  Amsterdam and Leiden and publication of research in scientific journals and presentation at scientific meetings

The Radboud University Nijmegen Medical Centre (UMCN) in the Netherlands is a top knowledge centre for academic medical research and healthcare. Research, education and patient care form the heart of our organisation. Over 9500 employees and 3000 students are shaping the future of healthcare and medical sciences.
 Our current project is part of the research consortium ALLOVIR (Amsterdam, Leiden, Nijmegen) funded by the Dutch Kidney Foundation (http://www.nierstichting.nl/asset/voor-professionals/biomedisch-onderzoek/consortia-2010/consortium-amst-nijm-lei-2010.pdf). This project  will be carried out at our Nephrology Research Laboratory, that is part of the multidisciplinary research institutes N4I (http://www.n4i.nl) and NCMLS (http://www.ncmls.nl).  A second project within the same research consortium is located at the Laboratory of Medical Immunology (Department of Laboratory Medicine)

Deadline: 31-03-2011

Contacts:

Email: L.Hilbrands@nier.umcn.nl

Phone number: +31 (0)24 3614761

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